Drenamin®

Drenamin is an adrenal function & energy production support supplement, with vitamins involved in production of neurotransmitters associated with emotional balance.*

• Involved in healthy adrenal gland functions*
• Supports energy production and metabolism*
• Contains vitamins that are involved in the production of neurotransmitters associated with emotional balance*
• Supports a healthy immune response i.e., to everyday environmental stressors*
• Contains a combination of key ingredients from Cataplex® C, Cataplex® B2, formerly known as Cataplex® G and Drenatrophin PMG® 
• Excellent source of riboflavin and niacin
• Good source of vitamin B₆ and antioxidant vitamin C 

How Drenamin Supports Adrenal Health

Vitamin C is found in high concentrations in the adrenal glands and plays a role in the natural stress response as a cofactor in the synthesis of catecholamines: the “fight or flight” hormones secreted by the adrenal glands.^1-3 Vitamin B6-dependent enzymes are also required for the biosynthesis of epinephrine and dopamine — two other important neurotransmitters.⁴

How Drenamin Impacts Emotional Balance

Dietary intake status of select nutrients — which include niacin (B3), riboflavin (B2), and vitamin B6, all of which are included in one serving of Drenamin — is associated with mental health status with regard to mood and optimal neurological functioning.^11-13 Vitamin B6 is a cofactor for the synthesis of GABA, serotonin, and dopamine.^14-15

How Drenamin Contributes to a Healthy Immune Response

Vitamin C is an antioxidant, which is critical to a healthy immune system by helping to manage oxidative stress, supporting the maturation of T cells, stimulating leukocyte function, and playing a role in natural killer (NK) cell activity.^5-8 Vitamin C is also important for white blood cell function as well as the maintenance and regeneration of cells.^6,8-9 The B vitamins riboflavin (B2), niacin (B3), and pyridoxine (B6) may also play a role in immune function.¹⁰

References:

1. Lykkesfeldt, J. & Tveden-Nyborg, P.11(2019). 
2. Padayatty, S.J., et al. Am J Clin Nutr 86, 145-149 (2007).
3. Patak, P., Willenberg, H.S. & Bornstein, S.R. Endocr Res 30, 871-875 (2004).
4. Parletta, N., Milte, C.M. & Meyer, B.J.. J Nutr Biochem 24, 725-743 (2013).
5. Conner, E.M. & Grisham, Nutrition 12, 274-277 (1996).
6. Manning, J., et al.. Antioxid Redox Signal 19, 2054-2067 (2013).
7. Wintergerst, E.S., Maggini, S. & Hornig,. Ann Nutr Metab 50, 85-94 (2006).
8. Carr, A.C. & Maggini, S.. Nutrients 9(2017).
9. Shaik-Dasthagirisaheb, Y.B., et al. J Biol Regul Homeost Agents 27, 291-295 (2013).
10. Peterson, C.T., Rodionov, D.A., Osterman, A.L. & Peterson, S.N. 12(2020).
11. Davison, K.M. & Kaplan, B.J. Can J Psychiatry 57, 85-92 (2012).
12. Parra, M., Stahl, S. & Hellmann, H. Cells 7(2018).
13. Kennedy, D.O.. Nutrients 8, 68 (2016).
14. Parletta, N., Milte, C.M. & Meyer, B.J. J Nutr Biochem 24, 725-743 (2013).
15. Head, K.A. & Kelly, G.S. Altern Med Rev 14, 114- 140 (2009).