MTHFR Gene Mutation Protocol

MTHFR Gene Confusion Explained

MTHFR Gene Mutation Protocol 

This protocol is designed to support the body’s ability to properly carry out the process of methylation. Methylation is one of the ways that the body makes sure the right genes are turned on, and the ones that we don’t want to get turned off. It means that even if we have a gene that predisposes us to a disease like Alzheimer’s, we can help that gene to stay silent by supporting healthy methylation.

“If you already know what MTHFR is, perhaps you know that you have a variant of this gene such as C677T or A1298C. If you have two copies of the C677T gene (this means you are homozygous for this variant) then the MTHFR enzyme’s activity can drop by 70-75%. If you have one copy of this gene (heterozygote) then the activity can be reduced by 33-35%. If you have two copies of the A1298C variant you may lose 39% of MTHFR activity. Methylation – What’s All the Fuss? – Kara Fitzgerald ND

But the presence of the MTHFR gene variant in your genetic structure does not mean that the variant has to express itself.

Your body has methods of turning off bad genes as much as it has the ability to stimulate the expression of good genes. This turning on and turning off of jeans is controlled primarily through environmental factors, the most important one being nutrition and food choices.

Methionine is essential for the synthesis of proteins and many other biomolecules required for survival. Rats fed a diet without methionine develop fatty liver disease which was show to be corrected by methionine supplements: [DIGESTIVE DISEASES AND SCIENCES; Oz,HS; 53(3):767-776 (2008)]. Since methylation is dependant on essential amino acids that you can only get from your diet, dietary methionine is essential for DNA methylation. Reduced DNA methylation results in genetic instability and aberrant gene expression.

Natural variation in this gene is common in healthy people. Remember, genes only express themselves when they get a chemical signal to do so. Just as genes can be harmed by outside influences, such as radiation and toxic chemicals, so can gene expression be helped by outside influences as well, the major one being nutritional status.

Supporting healthy methylation is actually a good anti-aging strategy since we tend to lose methylation capacity as we age since we do not eat the foods our great-grandparents ate so long ago.

Unless we are well versed in the subject, it is easy to misunderstand the vital importance of nutritionally dense foods, not just for our overall nutritional well-being, but for the vital control of our genetic structure especially when it comes to abnormal gene variants. Without a full-time cook following you around it can be difficult to get the proper food to support healthy methylation on a regular basis. I mean, who wants to gnaw on a liver organ, really?.

So we have put together a protocol that supports your body’s need to have healthy gene expression, replication, and to even help your body’s inner intelligence to know when to put the gene variant (mutation) back to sleep.


MTHFR Gene Mutation Protocol

the MTHFR Gene Mutation Protocol, however, we do not recommend nutritional support for non-patients using generic protocols. To access our Patient-Only content on The Forbidden Doctor website, you must start by filling out our Symptom Survey. Dr. Stockwell and his staff will review and provide customized supplement protocols for each new patient entering our practice. These personalized protocols will save you money immediately by guiding you to only the supplements you need. Once you are a patient who has been evaluated, you will be granted access to the Patient Portal and all of our Symptom Library protocols, including this one. There will also be a treasure trove of forbidden information that’s been kept from you for at least 90 years.

Take The Symptom Survey

Folic Acid-B12 (3, twice a day) or Cataplex B12 (3, twice a day)
Protefood (1/twice a day)
Zypan (3 with each meal)
Longlife Energy Enzymes (2, morning & night, on an empty stomach)
ProSynbiotic (3-6/day)
LivCo MediHerb (1, twice a day)
Sesame Seed Oil (2, twice a day)
Cyruta Plus (4, twice a day)
Enzycore (2 with each meal)

Questions about this protocol? Why not ask Dr. Jack and Mary directly? They will respond to patient texts at 801-556-1477 and emails to There are no “dumb questions” and you can expect absolute discretion and privacy.
  • The protocol above is designed to address your issues at the foundational level, and not to treat disease. This means, in our opinion, most of our health problems, short of accident or trauma, are of a dietary nutritional deficiency. The listed protocol or supplement provides your body with essential micro and macronut­­­­rients to help and assist normal nutritional balance.
  • Daily dosages are in ( ) parenthesis for most protocols; for example (6) means take 6 per day, but spread it out by taking half in the morning and a half in the evening. Some protocols will have more specific instructions to follow.
  • MediHerb products, shown in italics, often speed healing response and should be considered for most protocols unless contraindicated.
  • We recommend adding the General Health Daily Fundamentals pack to each protocol. This adds to the critical foundational nutrition each protocol needs. It contains Catalyn––an entirely whole-food and glandular broad-spectrum multivitamin, Trace Minerals-B12, and Tuna Omega-3 pearls for your DHA and EPA omega 3 fatty acids daily requirements.
  • Spacing out the daily doses throughout the day improves absorption and is strongly recommended.
  • Most supplements should be taken with food except for PMG’s, most calcium products, Gastrex, Chlorophyll Complex™, Okra Pepsin E3, Cholocol II, and Zymex II. Also, most herbs work more efficiently if taken away from food.
  • Be advised that these nutritional and herbal products are not intended as primary therapy for any disease, but rather to provide nutritional and herbal support to help normalize body physiology and repair.


Nothing presented on this website should be accepted or believed. That is because the FDA does not agree with or approve of any of it. Nor has the FDA evaluated anything written here.

This website is not literature, nor shall it be interpreted as such by anyone. In accordance with the right of freedom of the press guaranteed to us by the First Amendment of the U.S. Constitution, this website was created for informational purposes only.

The products mentioned in our podcasts and/or protocols on this website are not intended to take the place of medical care that you can get from a licensed medical physician. They are intended as nutritional support to help support the structure and function of your body and are not intended to diagnose, treat, cure, or even prevent any disease. It is provided as nutritional information to support your body.

This website is not intended to provide medical advice and nothing in it should be construed as a therapeutic recommendation or prescription for treating any disease or symptom; they are provided for nutritional support only. No person should attempt self-diagnosis of a disease or self-treatment of any kind but use these protocols for nutritional support only, and they should not discontinue any medication or therapy or make any health-related decisions without the advice of a licensed medical physician.

Dr. E. Jackson & Mary H. Stockwell, CGP, or any person employed by The Forbidden Doctor, LLC, or Dr. Jack Stockwell and Associates, LLC, disclaim any liability, loss, or risk incurred, directly or indirectly, as a result of implementing the protocols for nutritional support on this website.

Each person interested in a diagnosis should obtain a medical exam from a licensed medical doctor. In the said exam, the medical doctor can tell you if you are healthy enough to eat whole food and rebuild your body. Seriously. Rebuilding, excretion, and detoxifying can be rough.


Protocols, podcasts, recordings, charts, testimonials, documents, downloads, contained within this website are presented for informational purposes only, and are not meant to be a substitute for professional medical care or attention by a qualified practitioner, nor should they be construed as such. Always check with your doctor if you have any questions or concerns about your condition or before starting a new program of treatment. We at The Forbidden Doctor, LLC, (FD) cannot provide specific nutritional support or nutritional advice to individuals about their medical condition unless they have been evaluated in our clinic or through our virtual office. Forbidden Doctor is not responsible or liable, directly or indirectly, for any form of damages whatsoever resulting from the use (or misuse) of information contained in or implied by any podcast or document included in this website.

We have attempted to choose links to sites that we believe offer quality material and information. However, we do not endorse nor are we responsible for the material you find on other sites.

Any case reports, testimonials, documents, handouts, or protocols, described on this website, in articles, or on podcasts do not constitute guarantees of similar outcomes for current or future patients.

Users of this website are free to copy documents for personal use or to place hyperlinks to this website in their own documents and websites, although materials presented on these pages are copyrighted by the authors. These materials may not be sold or redistributed for profit, such as a multilevel or direct sales company, or any other “brick and mortar” for-profit business, without express written permission from Dr. E. Jackson or Mary H. Stockwell. This includes, but is not limited to, translations into foreign languages, mass archival as on a CD-ROM, and/or inclusion in commercially published compilations or for-profit (books).

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